Plain Language Summary

Creatine exerts its effect by increasing cellular hydration and by preserving methyl groups both of which are negatively affected in the alcoholic hangover.

 

Summary

Alcohol reduces creatine levels in the liver and simultaneously decreases its capacity to produce creatine. Supplementing creatine increases cellular hydration and reduces the need for methyl donation. Furthermore, creatine can protect nuclear and mitochondrial DNA from oxidative damage. [zotpressInText item=”{IC6UGACW},{RWVSVSHB},{T5X6TQ3E},{MRJ363DB},{BSP64I5B},{3CGVBIC2}” etal=”yes”]

Bibliography

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