Plain Language Summary

The Causes of a Hangover page describes the changes that occur in the human body during a hangover. It is the cornerstone of all the research on this site.

Each supplement has a dedicated page to illustrate the potential benefits of its use for a hangover. Many of them will include links to subheadings in the Causes of a Hangover page so you may read further.

Papers and references can be accessed either by following the links at the end of each page or by looking at my Zotero Library in full. Please feel free to contribute by joining Zotero and requesting access to the library.

Posts will have a more informal voice and include information for the non-biochemist or health professional. Consider them a broad overview of the site.


The targeted hangover effects can be grouped into several categories: oxidation, methylation, metabolic, and osmotic – none of which are entirely distinct. Each supplement is intended to circumvent specific effects of alcohol but some have multiple targets. For instance, dextrose can be used to alleviate metabolic acidosis [zotpressInText item=”{JSXMB2FX}” etal=”yes”]. Simultaneously, in conjunction with sodium, it can stimulate the uptake of water from the digestive tract [zotpressInText item=”{EPTWDTFV}” etal=”yes”] expediting fluid replacement.




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